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Glutathione peroxidases (GPxs) constitutes an enzyme family which has the ability to reduce free hydrogen peroxide to water and lipid hydroperoxides to their corresponding alcohols, and its main biological roles are to protect organisms from oxidative stress-induced damage. GPxs include eight members in different tissues of the body, and they play essential roles in carcinogenesis. However, the prognostic value of individual GPx in non-small cell lung cancer (NSCLC) remains elusive.

Distinct prognostic values of mRNA expression of glutathione peroxidases in non&ndash;small cell lung cancer

Distinct prognostic values of mRNA expression of glutathione peroxidases in non–small cell lung cancer