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Acetaldehyde dehydrogenase 2 ( ALDH2 ) and cytochrome P450 2E1 ( CYP2E1 ) have been associated with hepatocellular carcinoma (HCC) susceptibility and prognosis. The polymorphisms ALDH2 rs671 and CYP2E1 rs2031920 are reportedly correlated with the prevalence of HCC in other countries. The aim of this study was to investigate associations between ALDH2 and CYP2E1 , and HCC susceptibility in a population of Guangxi, southern China, an area with a high incidence of HCC.

cancer management and research

Genetic variants of &lt;em&gt;ALDH2&lt;/em&gt;-rs671 and &lt;em&gt;CYP2E1&lt;/em&gt;-rs2031920 contributed to risk of hepatocellular carcinoma susceptibility in a Chinese population