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Melanoma represents an important public health problem, due to its high case-fatality rate. Identification of individuals at high risk would be of major interest to improve early diagnosis and ultimately survival. The aim of this study was to evaluate whether MC1R variants predicted melanoma risk independently of at-risk phenotypic characteristics.

cancer management and research

&lt;em&gt;MC1R&lt;/em&gt; variants as melanoma risk factors independent of at-risk phenotypic characteristics: a pooled analysis from the M-SKIP project