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Large-scale observational studies based on existing medical databases may have an important role in studies of long-term effects of different treatments in prostate cancer patients if the coding of the treatment is valid. We therefore estimated the positive predictive value (PPV) and negative predictive value (NPV) of hospital codes for gonadotropin-releasing hormone (GnRH) agonist treatment and orchiectomies in the Danish National Patient Registry (DNPR).

Validity of the recorded codes of gonadotropin-releasing hormone agonist treatment and orchiectomies in the Danish National Patient Registry