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Aging of skin is associated with environmental factors such as ultraviolet rays, air pollution, gravity, and genetic factors, all of which can lead to wrinkling of skin. Previous reports suggest that the wound repair is impaired by the aging process and strategies to manipulate the age-related wound healing are necessary in order to stimulate repair.

clinical interventions in aging

Anti-aging effects of &lt;em&gt;Piper cambodianum&lt;/em&gt; P. Fourn. extract on normal human dermal fibroblast cells and a wound-healing model in mice