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Endothelial cell-cell junctions are strictly regulated in order to control the barrier function of endothelium. Vascular endothelial (VE)-cadherin is one of the proteins that is crucial in this process. It has been reported that phosphorylation events control the function of VE-cadherin. This review summarizes the role of VE-cadherin phosphorylation in the regulation of endothelial cell-cell junctions and highlights how this affects vascular permeability and leukocyte extravasation.

Phosphorylation at endothelial cell&ndash;cell junctions: Implications for VE-cadherin function

Phosphorylation at endothelial cell–cell junctions: Implications for VE-cadherin function