English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Correspondence: Matthew J Crowley HSRD and 2) future research needs pertaining to comparative effectiveness of ACE-I/ ARB in hypertension. Methods: Each of the two future research need prioritization projects was based on an AHRQsponsored comparative effectiveness review. For each project, we worked with the authors of the corresponding comparative effectiveness review to identify evidence gaps pertaining to the comparative effectiveness of ACE-I/ARB in the target condition, and performed an update of each review’s literature search strategy. We then formed a distinct stakeholder group for each future research need prioritization project and engaged each group in sequential exercises to rank the identified evidence gaps. Results: Although these projects engaged distinct stakeholder groups and relied upon different evidence bases, we noted near-complete overlap between the highest priority evidence gaps identified for each project. Stakeholders prioritized research: facilitating tailored treatment based on patient characteristics (eg, impact of demographics and comorbidities on ACE-I/ ARB effectiveness); targeting optimal implementation of ACE-I/ARB among patients most likely to benefit (eg, studies to improve evidence-based use, treatment adherence, and quality of life with ACE-I/ARB); and examining the impact of ACE-I/ARB on the incidence of new cardiovascular/metabolic diagnoses. Conclusion: Designing studies to address high priority evidence gaps for multiple disease conditions simultaneously may facilitate future comparisons of ACE-I/ARB, and may likewise be an appropriate strategy to improve research efficiency in other comparative effectiveness research scenarios.

Angiotensin-converting enzyme inhibitors and angiotensin-II receptor blockers: do future research needs differ across disease states?