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In the absence of EuroQol 5D data, mapping algorithms can be used to predict health-state utility values (HSUVs) for use in economic evaluation. In a placebo-controlled Phase II study of olaparib maintenance therapy (NCT00753545), health-related quality of life was measured using the Functional Assessment of Cancer Therapy - Ovarian (FACT-O) questionnaire. Our objective was to generate HSUVs from the FACT-O data using published mapping algorithms.

clinicoeconomics and outcomes research

Estimating health-state utility values for patients with recurrent ovarian cancer using Functional Assessment of Cancer Therapy &amp;ndash; General mapping algorithms