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Moisturizing products are commonly used to improve hydration in skin dryness conditions. However, some topical hydrating products could have negative effects on skin barrier function. In addition, hydrating effects of moisturizers are not commonly evaluated up to 24 hours after a single application. Hyaluronic acid (HA) and glycerin are very well-known substances able to improve skin hydration. Centella asiatica extract (CAE) could exert lenitive, anti-inflammatory and reepithelialization actions. Furthermore, CAE could inhibit hyaluronidase enzyme activity, therefore prolonging the effect of HA. A fluid containing HA 1%, glycerin 5% and stem cells CAE has been recently developed (Jaluronius CS [JCS] fluid).

clinical, cosmetic and investigational dermatology

The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and &lt;em&gt;Centella asiatica&lt;/em&gt; stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study