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The major economic importance of neonatal infectious diarrhoeas in calves have justified for a few years the development of control programmes combining both sanitary and medical aspects [7]. The importance of immunity conferred through colostrum and milk has been demonstrated [1] [2] [8]. The vaccination of pregnant cows revealed, in the field, as the most efficient mean to reach a high colostrum and milk immunity [3] [4] [5] [10]. The etiology of neonatal infectious diarrhoeas in cattle is now well-determined different types of colibacilli having well-characterized attachment or virulence factors are now isolated; viruses, rotavirus and coronavirus, have also been evidenced [6] [9] [11] [12]. The authors present the results obtained during a controlled clinical trial by using an inactivated vaccine, adjuvanted with aluminium hydroxyde and saponin. This vaccine is indicated for vaccination of pregnant cows.

Evaluation of An Associated Inactivated Vaccine Against Neonatal Diarrhoeas Caused by Colibacilli, Rotavirus and Coronavirus