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An analogue of luteinizing hormone-releasing hormone, [Des-Gly-NH210, Pro-ethylamide9]-LH-RH, was recently synthesized1) and found to be highly potent for the release of LH and FSH from the pituitary of rats in vitro2) and in vitro1,3) and of men in vivo4), for the release of LH from the pituitary of cattle in vivo5), and for the induction of ovulation in rats1,3), rabbits3) and ckickens6). The present experiments were preformed to elucidate the gonodotropin-releasing activity of this analogue on chicken pituitaries in vitro. [Des-Gly-NH210, Pro-ethylamide9]-LH-RH, which was generously supplied by Takeda Table 1. Conadotropic activity of medium in which cock pituitaries were incubated in vitro with and without [Des-Gly-NH210, Pro-ethylamide9]-LH-RH

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&lt;i&gt;In Vitro&lt;/i&gt; Release of Gonadotropins from the Pituitary of Cocks by an Analogue of Luteinizing Hormone-Releasing Hormone: [Des-Gly-NH&lt;sub&gt;2&lt;/sub&gt;&lt;sup&gt;10&lt;/sup&gt;, Pro-ethylamide&lt;sup&gt;9&lt;/sup&gt;]-LH-RH