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This study aimed to investigate the effect of replacing fat in broiler grower diet with sucrose combined with supplementation of the synthetic amino acid lysine on growth performance, gastrointestinal morphology, and blood biochemical parameters in broiler chickens. Broilers were raised for 21 days and then divided into two treatment groups ( n =24 in each group). Two dietary treatments were used: corn-soy-based diet with oil (control) and corn-soy-based diet formulated with sucrose (3.30%) and lysine hydrochloride (3.36%). The experimental period was 21 days (from 21 to 42 days of age). At the end of week 6, all the birds in each treatment were slaughtered via neck slit, defeathered, and eviscerated for carcass and intestinal morphological characterization. Blood samples were collected to measure blood lipoprotein, triglyceride, and cholesterol levels. The results showed that supplementation of sucrose and lysine hydrochloride to broiler ration significantly ( P &lt;0.05) decreased feed intake by half and reduced average daily gain during the study period compared to those observed in broilers fed control diet. Further, this supplementation significantly altered gastrointestinal morphology and blood lipoprotein (HDL and LDL) and total cholesterol levels. In conclusion, corn-soy-based diet fortified with sucrose (3.30%) and lysine hydrochloride (3.36%) within current nutrient specifications has a negative effect on broiler growth performance.

journal of poultry science

Effects of Sucrose-based High-lysine Diet on Blood Chemistry, Growth Performance, and Gastrointestinal Morphology of Broiler Chickens During the Growing Stage