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Compositions of oxysalt, sulfosalt, seleniosalt, tellurisalt, and fluosalt minerals all follow the same generalizable patterns with regard to hardness or softness of cations, and with regard to ionic potential. For example, the hard F 1-  anion forms simple fluosalt minerals (fluoborates and fluosilicates) with hard cations. The relatively hard O 2-  anion forms simple oxysalts (e.g., sulfates and arsenates) largely with hard to intermediate cations. On the other hand, the softer S 2-  anion forms sulfosalt minerals almost entirely with intermediate to soft cations, and the still softer anions Se 2-  and Te 2-  form seleniosalt and tellurisalt minerals with an even more predominately soft suite of cations. Thus, across all these classes of minerals, harder anions generally form minerals with harder cations, and softer anions form minerals with softer cations.

Patterns in the compositions of oxysalt and sulfosalt minerals, and the paradoxical nature of quartz