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Correspondence : Malyn CHULASIRI two flavones, hispidu]in (6-methoxy-5,7,4'-trihydroxyflavone) and hortensin (3,4Ldihydroxy-6,7dimethoxyflavone), Their chemical structures are shown in Fig 1. A number ef natural and synthetic flavonoids have been tested for mutagenic andlor antimutagenic potentialsC2・3・S・S・ie・iS・i7i, but neither hispidulin nor hortensin has. In this investigation, the mutagenic effects of these two compounds in Salmonella typhimt-i'ium strains :TIA98 and TAIOO were studied. IR addition, hispidulin and hortensin were examined for antimuta-

MUTAGENICITY AND ANTIMUTAGENICITY OF FLAVONOIDS EXTRACTED FROM MILLINGTONIA HORTENSIS L.