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Diabetic foot is one of the common complications associated with diabetes. The treatment of metformin may help in reducing the prevalence of diabetic foot ulcer among diabetic patients. Study objectives: To investigate the prevalence of diabetic foot ulcer among diabetic patients attending out-clinic patients at Jordanian Royal Medical Services and to investigate the impact of metformin treatment in the development of diabetic foot ulcer. Methodology: A retrospective design was involved to collect data from files of diabetic patients. Study variables included some demographic variables such as gender and age; and clinical variables such as duration of diabetes, treatment with metformin, and the status of diabetic foot ulcer. Data were collected and entered into SPSS version 20 for analyzing purposes. Statistical analysis includeddescriptive features such as frequency, percentage, mean and standard deviation. The relationship between variables was examined using various statistical models such as ChiSquare test, One Way Anova, and Pearson’s correlation. The significance was accepted if p< 0.05. Results: Study included 62 diabetic patients; the mean age was 56.95±11.98 years. The males were 33 (53.2%), the duration of diabetes was 7.5±5.86 years; about 66% of patients were prescribed for metformin, the mean of metformin dose was 1617.32±649.49 mg, and the prevalence of DF was 8.1%. No significant relationships were observed between DF and each of gender and metformin use (p>0.05). Both One Way Anova Test and correlation test showed that DF was significantly associated with DF. Conclusion: The present study showed that treatment by metformin is associated significantly with metformin dose and could help diabetic patients against developing DF.

THE IMPACT OF TREATMENT WITH METFORMIN ON DIABETIC FOOT ULCER AMONG DIABETIC PATIENTS VISITING JORDANIAN ROYAL MEDICAL SERVICES