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Each year, over 300,000 neonates born with sickle cell disease (SCD) and half of them die before the age of 5 years. This disease is more pronounced in developing countries 1 .The prevalence of sickle cell carriers found to be more among different tribal groups which varies from 1 to 40 % in India . Majority of these tribal groups live in rural areas and not able to afford expensive proposed therapies such as the medullar implantation and repeated blood transfusion which increases our interest to investigate a novel and safe medicine for SCD. SCD is inherited chronic disease in International Journal of Pharma Research and Health Sciences

In-Vitro Anti-Sickling Activity of Selected Medicinal Plant to Explore Herbal Remedies for Sickle Cell Anemia