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Contrast enhanced imaging for focussing a differential diagnosis is well known in central nervous system (CNS) imaging. Specific patterns of contrast enhancement on Magnetic resonance imaging (MRI) can be used as a signature to diagnose many conditions with great confidence. This study highlights the use of patterns of contrast material enhancement in non traumatic brain lesions on MRI Brain, to define the locations and appearances of the lesions with specific patterns and narrow the differential diagnosis to a specific etiology. Method and Materials: This was a record based cross sectional study of 113 cases referred for contrast enhanced MRI of brain done from September 2017 to august 2018. Any patient whose MRI Brain showed contrast enhancing lesion(s) and/ or detected incidentally was included without any exclusion to specific age or gender. Any patient with enhancing lesions in brain secondary to alleged history of trauma were excluded. All the data collected were compiled as per patient and contrast enhancement pattern in Microsoft excel and descriptive statistics in the form of percentage,and mean were represented in the form of tables and charts. Results: Of the 133 instances of enhancement patterns detected: 56.63% (64) of the enhancement patterns were infective etiology, most common being smooth thin ring enhancement(25.56%, 34 cases); 36.28% (41) neoplasms of which pachymeningeal enhancement(14.28%) was most common. Conclusions: Specific enhancement patterns of different etiologies enable non-invasive diagnosis of neurological lesions and improve patient care by instituting prompt treatment and minimizing the unnecessary investigations.

Contrast Enhancement Patterns of Non-Traumatic Brain Lesion: A Diagnostic Approach on Magnetic Resonance Imaging