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Stroke is a second leading cause of death globally and is a major cause of long term disability. Study aimed to measure the cerebral infarct volume by MRI using ABC/2 method and its correlation with clinical outcome using NIHSS score. Material and Methods: This was a prospective study done over a period of one and half years. About 60 adult cases of acute ischemic stroke, who underwent MR imaging (DWI sequence) in department of Radio-Diagnosis, M.S.Ramaiah Medical College, Bengaluru, were included in the study. The cerebral infarct volume caw calculated on MRI study. The National Institute of Health Stroke Severity score was done in all the cases. The correlation between cerebral infarct volume and NIHSS was seen at the end of 90 days for clinical outcome. The current study evaluates the relationship between NIHSS score and infarct volume and how it can be used to assess the outcome of the neurological severity ninety days after acute stroke. Results: Out of 60 cases, clinical outcome was good in 41 cases with an infarct volume between 10-39 cc, poor in 13 cases with an infarct volume between 40-89 cc and 6 patients died with an infarct volume above 100 cc. Poor outcome was seen in cases with NIHSS score above 25. Conclusion: The infarct volume between 10-40 cc showed good prognosis, infarct volume between 40 and 89 cc showed poor prognosis while volume above 100 cc resulted in 100% mortality. As the infarct volume increases the NIHSS score also increases on follow up study predicting the clinical outcome with the infarct volume estimated at the onset of stroke. From this study we conclude that the acute stroke volume can be used to predict the stroke severity by using NIHSS score.

Measurement of Cerebral Infarct Volume by Magnetic Resonance Imaging using ABC/2 Method and its Correlation with Clinical Outcome using NIHSS Score