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Metabolic syndrome is increasing rapidly all over the world. There has been an increasing amount of evidence to suggest that metabolic syndrome is associated with many endocrine disorders, including thyroid disorders. The presence of thyroid disorders in patients with metabolic syndrome may increase the risk of cardiovascular disease. This study was carried out to evaluate for thyroid disorders in patients with metabolic syndrome and to assess its connection with individual parameters of metabolic syndrome. Material and methods: A prospective observational study was done for a period of 20 months in our tertiary care hospital. All the patients fulfilling the International Diabetes Federation criteria for metabolic syndrome were enrolled. Sociodemographic data, anthropometric measurements, blood pressure, were recorded. Blood samples were analyzed for glucose, triglycerides, high-density lipoprotein, cholesterol, and thyroid hormones (Thyroid-stimulating hormone and Thyroxine) in fasting state. Results: Among 92 patients studied, thyroid dysfunction was noted in 18.47% (n=17). Subclinical hypothyroidism (14.13%, n=13) was the most common thyroid dysfunction noted. Overt hypothyroidism was found in 4.34% (n=4) of subjects. The prevalence of thyroid dysfunction was more in females (15.21%, n=14) compared to male patients, which was statistically significant (p=0.007). The association of thyroid dysfunction with each parameter of metabolic syndrome was not statistically significant. Conclusion: Thyroid dysfunction is common among patients with metabolic syndrome. A higher prevalence of subclinical hypothyroidism, especially among female patients with metabolic syndrome, emphasizes the need for careful evaluation of thyroid disorders in patients with metabolic

Assessment of Thyroid Dysfunction in Patients with Metabolic Syndrome and its Correlation with Individual Parameters of Metabolic Syndrome