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Esophageal varices are generally the most common clinical manifestation of portal hypertension in Patients of liver cirrhosis. Most common causes of death in liver cirrhosis are hemorrhage from esophageal varices. The present study has been carried out to identify clinical, biochemical and ultrasonographic parameters which might non‐invasively predict the existence and the risk of variceal bleed. Material and Methods: The present prospective observational study was conducted in 2 years among 100 patients suffering from liver cirrhosis above 18 years of age. Detailed history, clinical examination, investigations to fulfill the inclusion and exclusion criteria of all patients was taken. Different non endoscopic parameters were taken Plateletcount, Coagulation profile, Ultrasonography whole abdomen, Child-PughTorcotte (CPT) Score, AST to platelet ratio index (APRI) for the detection of esophageal varices and its grading in liver cirrhosis patients which was confirmed by endoscopy. Results: There was significant association of presence of esophageal varices in liver cirrhosis patients with presence of icterus, presence of ascites,presence of splenomegaly, grade of Child Pugh Score, AST to Platelet rationdex (APRI score) Prothrombin Time and International Normalized Ratio(PT/ INR), mean TB (mg/dl), mean spleen size. Conclusions: The result of present study concluded that some parameters are strongly associated with grades of varices and could be useful for early detection and subsequent management of varices.

Evaluation of Non-endoscopic Parameters for the Detection of Esophageal Varices in Patients of Liver Cirrhosis, Confirmed by Endoscopy