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Intravenous Regional Anaesthesia (IVRA), though safe and effective, the search continues for an ideal analgesic devoid of side effects, which can be added to IVRA local anaesthetics to improve perioperative analgesia. This study was undertaken to assess the analgesic effectiveness of adding Clonidine to Lignocaine in IVRA in patients of hand and forearm surgeries. This was, further, compared with the addition of Tramadol and plain Lignocaine Material and Methods: This study was carried out on patients aged 18 to 60 years belonging to ASA grade I and II, undergoing upper limb surgeries lasting for less than 90 minutes. They were divided in three groups: Clonidine Group, Tramadol Group and the plain Lignocaine Group. Intraoperative and postoperative (up to 4 hours) analgesic parameters were observed. Results: It was found that the Clonidine was much better than Tramadol, which was in turn better than plain Lignocaine in terms of prolongation of sensory and motor action, tourniquet tolerance and duration of analgesia, without any complications. Conclusion: Addition of Clonidine to IVRA significantly improves perioperative analgesia.

A Comparative Study on the Effects of Clonidine Plus Lignocaine, Tramadol Plus Lignocaine and Plain Lignocaine for Intravenous Regional Anesthesia