English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The present study was undertaken to evaluate pharmacokinetics of ferulic acid following oral administration of ethyl ferulate alone and in combination with piperine in rats. Following oral administration of ethyl ferulate and in combination with piperine, the mean peak plasma ferulic acid concentration of 18.38  1.38 vs 15.27  1.18 g/ ml was achieved at 0.25 h. Plasma concentration of ferulic acid at 0.5 h differ significantly (p<0.05) and plasma concentration of ferulic acid at 0.08 h, 0.25 h, 0.75 h and 1 h did not differ significantly. All pharmacokinetic parameter of ferulic acid did not differ significantly except volume of distribution (1.25 ± 0.12 vs 2.85 ± 0.57 L/ kg) and total body clearance (7.35 ± 0.57 vs 17.19 ± 1.59 L/h/kg).The study indicates rapid absorption and clearance of ferulic acid from body following oral administration of ethyl ferulate alone and in combination with piperine in rats.

Pharmacokinetics of ferulic acid following oral administration ethyl ferulate alone and in combination with piperine in rats