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Introduction: the management of HCC in assiut governorate is affected by many factors that would affect the choice and effectiveness of treatment. Aim of the work: to identify the different lines of management of HCC and factors associated with them. Methods: retrospective study that included 146 patients with primary hepatocellular carcinoma (HCC), admitted to Assiut university hospital and El Rajhi hospital during the period from January 2012 to December 2014. Results: the main lines of HCC management included 5 lines: surgery (resection/transplantation), local ablation, TACE, chemotherapy and Best supportive care. The most significant factors that affected treatment choice and results were Child pugh score, primary tumor size and multiplicity. Conclusion: The best cure rate was found in small or single lesions or child pugh score A managed with surgical resection. TACE was the most widely used modality.lesions more than 5 cm or multiple lesions or child pugh score B or C were associated with chemotherapy and best supportive care.

A Retrospective Study on Different Treatment Modalities of Hepatocellular Carcinoma in Assiut Governorate