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The aim of this study was to evaluate the mechanism by which EMF therapy can interfere with the modified immune and oxidative reactions by the experimental approach on the lab animals. In vivo and vitro experiment was carried out on 60 Wistar rats that were divided in 4 groups as following: 1. Control-group tested on the 10th day; 2. LF-EMF-exposed group tested on the 10th day; 3. Group that received intradermic Staphylococcus aureus culture (SA) and was tested on the 10th day; 4. Group that received intradermic SA and was treated with LFEMF and was tested after 10 days. The rats were exposed to 50 Hz, 1 mT. Splenic lymphocytes and alveolar macrophages for the cellular cultures were harvested. The following parameters were assessed: a) 3HTdR incorporation test; b) Macrophage inhibition factor (MIF) assay; c) IL-1 assay; d) TNF-assay; e) Chemiluminescence assay; f) Phagocytosis assay. The 3HTdR incorporation test, tests targeting the cytokine’s activity and the phagocytosis test point out a partial reversibility of the values in the EMF-exposed groups that was treated with staphylococcus cultures. Our experiment reveals that the EMF interferes with the immune and oxidative systems, becomes chronic and plays a key role in the development of serious diseases. The EMF-therapy can be beneficial in reducing the inflammation by interfering with the inflammatory molecules and surface receptors.

ELECTROMAGNETIC FIELD THERAPY AND IMMUNE MECHANISMS WHICH ARE INVOLVED IN ANTI-INFLAMMATORY RESPONSE