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The study presented in this paper concerns the extractability of rutin into an aqueous 1-butyl-3-methylimidazolium chloride (BMIM-Cl) solution. The effects of the concentrations of BMIM-Cl, amounts of Flos Sophorae Immaturus (FSI), extraction temperature and time on the rutin yield were examined. Under optimized extraction conditions, the rutin yield obtained by using aqueous BMIM-Cl corresponded to that obtained by using methanol. A newly established extraction method, followed by HPLC with ultraviolet detection, was applied to FSI samples with good recoveries and high repeatability.

Extraction of Rutin from Flos Sophorae Immaturus with an Aqueous 1-Butyl-3-methylimidazolium Chloride Solution