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(furanyl)methylene]hydrazide (I) is used for the treatment of acute and chronic diarrhea, gastroenteritis, and colitis. Analytical methods used for the determination of nifuroxazide include titrimetric1, complexometric2, ultraviolet spectrophotometric3, and HPLC.3 At present, only a few studies dealing with nifuroxazide polarographic behavior have been reported and the authors seems to have encountered only two waves.4–6 In this work, the polarographic behavior of nifuroxazide and its analytical utility have been investigated.

Determination of Nifuroxazide in Capsules by Differential Pulse Polarography