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1. Overview 2. Diagnosis and treatment process for esophageal cancer 3. Principles of diagnosis and treatment 3.1 Clinical diagnosis 3.1.1 Risk factors and high-risk group 3.1.2 Clinical manifestations 3.2 Examinations 3.2.1 Lab tests 3.2.2 Tumor marker 3.2.3 Images 3.2.4 Endoscopy 3.2.5 Other tests 3.3 Diagnosis 3.3.1 Clinical diagnosis 3.3.2 Pathological diagnosis 3.4 Differential diagnosis 3.4.1 Other malignancies of esophagus 3.4.2 Benign tumors or tumor-like lesions  of esophagus 3.4.3 Benign esophageal diseases 3.5 Pathological classification and staging 3.5.1 Segment of esophagus 3.5.2 Macroscopic type of esophageal carcinoma  (Appendix A) 3.5.3 Pathological subtype and classification 3.5.4 Types of specimen and principle of specimen  fixation 3.5.5 Principle of tissue dissection and description 3.5.6 Content and principle of pathological report 4. Standard treatment of esophageal carcinoma 4.1 Principle of treatment 4.2 Surgery 4.2.1 Principle of surgery 4.2.2 Indication of surgery 4.2.3 Contraindication of surgery 4.2.4 Follow-up 4.3 Radiotherapy 4.3.1 Indications for radiotherapy 4.3.2 Assessment of radiotherapy 4.3.3 Principle of radiotherapy 4.3.4 Dose 4.3.5 Normal tissue tolerance dose-limits 4.3.6 Concurrent chemotherapy regimens and dosing 4.3.7 Radiotherapy associated complications 4.3.8 Follow-up after radiotherapy 4.4 Medical management 4.4.1 Indications of chemotherapy for esophageal cancer 4.4.2 Assessment before chemotherapy 4.4.3 Regimens and dosing 4.4.4 Assessment of therapeutic effect 4.4.5 Prophylaxis and treatment of chemotherapy  associated complications 4.4.6 Follow-up after chemotherapy 4.4.7 Progress in molecular targeted therapy and  immunotherapy 4.4.8 Supportive and palliative treatment 4.5 Principle of early-stage cancer/precancerous disease of esophagus and endoscopic treatment 4.5.1 High-risk group of esophageal cancer 4.5.2 Methods of screening 4.5.3 Preoperative assessment of endoscopic treatment on  early stage esophageal cancer 4.5.4 Endoscopic therapy for early-stage esophageal  carcinoma 4.5.5 Follow-up for high-risk group and patients underwent  endoscopic therapy 4.6 Treatment model for esophageal cancer 4.6.1 Stage I (T1N0M0) 4.6.2 Stage Ib, stage II and part of stage IIIa  (T1b−3N0M0, T1−2N1M0) 4.6.3 Stage III (T3N1M0, T4N0−1M0) 4.6.4 Stage IV (any T, any N, M1, N3 or T4b) 4.7 Traditional Chinese Medicine Guidelines

Chinese guidelines for diagnosis and treatment of esophageal carcinoma 2018 (English version)