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Objective: To evaluate the impact of the inclusion of tiotropium in the treatment of chronic obstructive pulmonary disease (COPD) using real world data (DATASUS) and statistical analyzes, comparing hospitalization rates and costs associated with hospitalization in states where tiotropium is reimbursed in their treatment guidelines compared to states where tiotropium is not included. Method: A retrospective historical study conducted between 2013 and 2015, based on data obtained from DATASUS, state public purchasing portals and State Health Secretariats. All indexes were normalized by the number of the population, according to the IBGE updated data. The Z tests were used to evaluate the statistical significance of the results. Results: The combined analysis of the tiotropium reimbursed group presented 52.4% fewer hospitalizations compared to the tiotropium Recebido em: 12/03/2018. Aprovado para publicação em: 31/03/2018. 1. Boehringer Ingelheim, São Paulo, SP, Brasil. 2. Heads in Health, São Paulo, SP, Brasil. Instituições participantes: Heads In Health e Boehringer Ingelheim do Brasil. Instituição onde o trabalho foi executado: Heads In Health – Rua Vergueiro, 2253, cj. 1.011, Vila Mariana, São Paulo, SP. CEP: 04101-100. Informações sobre auxílios recebidos sob a forma de financiamento, equipamentos ou medicamentos: Este estudo foi financiado pela Boehringer Ingelheim do Brasil. Autor correspondente: Natália Bolzachini Santoni. Av. das Nações Unidas, 14171, 18o andar, torre B, Vila Gertrudes, São Paulo, SP. CEP: 04794-000. E-mail: natalia.santoni@boehringer-ingelheim.com ARTIGO ORIGINAL ORIGINAL ARTICLE Palavras-chave: doença pulmonar obstrutiva crônica, tiotrópio, internações, custos

jornal brasileiro de economia da saúde

Índice de hospitalização e custos associados à doença pulmonar obstrutiva crônica (DPOC) entre estados que padronizaram versus que não padronizaram o tiotrópio – dados do mundo real