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A single “typo” in the genome can have profound consequences on an organism’s biology. Identifying the protein changes that accompany these genomic typos is a fundamental challenge in bioinformatics. Tools exist for identifying genomic variants and predicting their associated polypeptide-level changes, however, wrangling genomic variant calls and protein variant predictions across thousands of samples remains a substantial challenge. cerebra addresses this need by offering a fast and accurate framework for summarizing genomic variant calls and protein variant predictions across many samples.

cerebra: A tool for fast and accurate summarizing of variant calling format (VCF) files