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N May of 1958, histoplasmin testing of children attending school (kinder. garten through 12th grade) in the principal communities of Washtenaw County, Michigan, brought to light a focus of hyperendemic sensitivity to histoplasmin in Milan,' where about 61 per cent of 1,300 school children had positive histoplasmin tests. In the other communities, the relative frequency ranged from about 3 per cent to 11 per cent, with an average of about 8 per cent for some 7,800 children. Subsequent histoplasmin testing of children in the Milan School District at approximate six-month intervals from May, 1959, through October, 1962, was done on a selective basis. Epidemiologic investigations were begun in August, 1959, and by August, 1960, the point source of the fungus dissemination was tentatively identified as being located within the bounds of a starling roost, which included a portion of the bare earth area on the north side and to the rear of the public Junior High School.2 Preliminary results M.D., M.P.H., F.A.P.H.A.; and Katherine M.

Observation on the decline of histoplasmal infections in school children: Milan, Michigan, 1958-1968.