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Hepatocellular carcinoma (HCC) is claimed to be one kind of the most common malignancy in background with a high morbidity of hepatitis virus infection,which is also the third commonest cause of cancer-associated mortality in China for its aggressive recurrence and metastasis (1-4). Despite advancement of adjunctive treatment, surgery and transplantation have taken benefits for HCC patients over decades, the survival outcome of HCC still be unsatisfactory with main contributors of relapse or metastasis, especially for patients complicated with severe cirrhosis (5-7). Radiofrequency ablation (RFA) has been developed as an effective treatment approach for HCC patients with severe cirrhosis, which also had benefits in terms of complications and hospitalization duration (8-10). HBV infection related liver fibrosis or cirrhosis has been confirmed as a significant factor relating to prognosis of HCC (11-13). Thus, accurately quantitative evaluation of the fibrosis is curial for Original Article

Prognosis value of liver stiffness measurements by 2D-SWE in primary HBV-positive hepatocellular carcinoma following radiofrequency ablation