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Although the incidence of malignant pleural mesothelioma (MPM) is low, most lesions are extensive, with obvious symptoms and a poor prognosis. Trimodality therapy including chemotherapy, extrapleural pneumonectomy (EPP), and hemithorax radiotherapy, has shown promising results in patients with medically operable MPM, with a median survival period of 19–33.5 months in prospective studies (1-5). Findings from a contemporary cohort demonstrated that lung-sparing extended pleurectomy/ Original Article

translational cancer research

Dosimetric evaluation of helical tomotherapy and volumetric-modulated arc therapy for malignant pleural mesothelioma: a planning study for dose escalation