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Department of Respiratory Medicine, Affiliated People’s Hospital of Jiangsu University, Zhenjiang 212002, China; Clinical Medicine College of Jiangsu University, Zhenjiang 212013, China; Department of General Surgery, Affiliated People’s Hospital of Jiangsu University, Zhenjiang 212002, China Contributions: (I) Conception and design: All authors; (II) Administrative support: X Bu; (III) Provision of study materials: Y Yan; (IV) Collection and assembly of data: R Zhang, Y Zhang; (V) Data analysis and interpretation: R Zhang, X Zhang, A Zhang; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. These authors contributed equally to this work. Correspondence to: Xuefeng Bu, PhD. Department of General Surgery, Affiliated People’s Hospital of Jiangsu University, DianLi Road NO.8, Zhenjiang, Jiangsu 212002, China. Email: xuefengbu05@163.com.

translational cancer research

Recombinant Newcastle disease virus expressing human IFN-λ1 (rL-hIFN-λ1) inhibits lung cancer migration through repolarizating macrophage from M2 to M1 phenotype