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The article describes the radioguided localization technique of small lesions (maximum nodule diameter  99m technetium macro-aggregate albumin diluted with iodized contrast medium. This allows the stability of the radiotracer in the lung for up to 18 hours for an optimal planning of the surgical resection. A CT scan was performed to confirm the precise staining. Then a VATS with three ports was performed and the gamma detector was inserted inside the chest to localize the tracer and the parenchyma was grasped in its correspondence. After a double check of the tracer’s position with the gamma detector, the resection was performed and the sample was sent for histologic examination (frozen section). In case of diagnosis of lung cancer, a VATS lobectomy was performed.

Commentary on the article “Radioguided video-assisted resection of non-palpable solitary pulmonary nodule/ground glass opacity: how to do it”