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Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, China; Department of Traumatology and General Surgery, Chun’an County Hospital of Traditional Chinese Medicine, Hangzhou, China Correspondence to: Honghui Wang. Department of Traumatology and General Surgery, Chun’an County Hospital of Traditional Chinese Medicine, No. 1 Xin’an West Road, Qianhu Island, Chun’an County, Hangzhou, China. Email: ch20588@163.com. Response to: Yang S, Xue Y, Liu J, et al. Is fibrinogen plasma level a risk factor for the first 24-hour death of medically treated acute type A aortic dissection patients? Ann Transl Med 2020;8:1015.