Open AccessCharacterization of antibody response against 16kD and 38kD of M. tuberculosis in the assisted diagnosis of active pulmonary tuberculosis
Author(s) -
Xiaohui Hao,
Jie Bai,
Yingying Ding,
Jinhong Wang,
Yidian Liu,
Lan Yao,
Wei Pan
Publication year - 2020
Publication title -
annals of translational medicine
Language(s) - English
Resource type - Journals
eISSN - 2305-5847
pISSN - 2305-5839
DOI - 10.21037/atm-20-5476
Subject(s) - tuberculosis , antigen , mycobacterium tuberculosis , serology , medicine , antibody , pulmonary tuberculosis , active tuberculosis , immunology , pathology
This study found that the detection effect of 16kD and 38kD antigens was similar in confirmed cases and clinically diagnosed cases of pulmonary tuberculosis, and that the detection effect needs to be further improved. The combined detection of the two antigens showed a significantly better detection effect than the two antigens alone, suggesting that the combined detection of multiple antigens can be used for serological diagnosis of infection in clinic.
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