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BackgroundRestoration of the acetabulum during total hip arthroplasty in adults with developmental dysplasia of the hip (DDH-THA) and resumption of hip function remain major challenges. Herein, a new patient-specific instrument (PSI) was developed that uses the superolateral rim of the acetabulum as a positioning marker to assist surgeons in adult DDH-THA.MethodsFrom January 2017 to October 2018, 104 adult DDH patients were randomized to either the PSI group or conventional operation (CO) group, and further divided into eight subgroups by stratified random sampling using Crowe's classification. Complications, Harris hip scores (HHS), and X-ray results were recorded at 3 and 12 months after surgery.ResultsWith the exception of anteversion in CO-Crowe II group patients, there was no difference in the accuracy of cup placement and orientation between the PSI and CO groups in Crowe I and II DDH patients. With the exception of percentage of acetabular cup coverage (PACC) and the qualification rate of Crowe IV PACC patients, among all Crowe III and IV DDH groups, all postoperative indexes of cup orientation and positioning exhibited significant differences between the PSI and CO groups; however, no significant differences were observed in Crowe I and II DDH patients.ConclusionsCompared with conventional methods, the new PSI-assisted surgical method improved the accuracy of placement and orientation of the acetabulum and cup prosthesis, optimized the surgical process, reduced complications, and contributed to quicker recovery of hip function after surgery in adults with Crowe III and IV DDH-THA, but little difference was noted for those with Crowe I and II DDH.

annals of translational medicine

Patient-specific total hip arthroplasty is superior to conventional methods for Crowe III and IV adult developmental hip dysplasia: a randomized controlled trial