Open AccessDexmedetomidine attenuates cerebral ischemia-reperfusion injury in rats by inhibiting the JNK pathway
Author(s) -
Bingxiao Zhao,
Da Li,
Shuchi Zhang,
Long He,
Yanqiu Ai
Publication year - 2021
Publication title -
annals of palliative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.546
H-Index - 19
eISSN - 2224-5839
pISSN - 2224-5820
DOI - 10.21037/apm-21-1218
Subject(s) - dexmedetomidine , medicine , reperfusion injury , ischemia , anesthesia , pharmacology , cardiology , sedation
Cerebral ischemic reperfusion injury (CI/RI) is a common cerebrovascular disease with high morbidity and disability that threatens human health. This study was conducted to explore the effects of dexmedetomidine (Dex) on the c-Jun N-terminal kinase (JNK) pathway in CI/RI, and to provide a theoretical basis for the recovery of brain function after cerebral ischemia.
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