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The Tibetan population is minority in southwest China, and data on the psychological states of Tibetan cancer inpatients are not available. The study participants included Tibetan and Han cancer inpatients, and their depression and anxiety were investigated and analyzed to understand the psychological states of Tibetan cancer patients. The aim of the present study was to understand the incidence of depression and anxiety among Tibetan cancer inpatients, and the factors affecting their depression and anxiety.