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Patients with primary Sjögren's syndrome (pSS) often suffer from sleep disturbance. Studies suggest it may be related to symptoms, including xerostomia and dry eyes. Clinical studies have confirmed that hydroxychloroquine (HCQ) has a definite effect on pSS, but there is no clear report about its effect on sleep disorders in pSS patients.

Long-term hydroxychloroquine therapy improves the quality of sleep in patients with primary Sjögren’s syndrome: a real-world study