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The high prevalence of musculoskeletal diseases (MSDs) in certain populaion groups may cause a high consumption of non steroideal antiinflamatory drugs (NSAIDs). The present study aims to identify the continuous consumers of NSAIDs in a cohort of workers, who mainly perform manual tasks, analyzing the use of other drugs prescribed for the treatment of musculoskeletal pain (MSP). Material and methods: Observational retrospective study. It has been analyzed data of all subjects, included on the AWHS (Aragon Workers Health Study) cohort, who received at least one NSAID prescription during 2016. It has been calculated the rate of use of NSAID, as well as the number of DDD per 1000 inhabitants per day (DHD). It has been identified continuous consumers, as those who used 182 defined daily dose (DDD) or more. For this group, it has been analyzed all prescriptions including other drugs used to treat MSP. Results: The rate of use of NSAIDs in the AWHS cohort in 2016 was 41.6% (95% CI: 40.1%-42.7%), being higher in women (47.0%, 95% CI: 41.9%52.1%). 5.7% of NSAID users were continuous consumers. Among them, etoricoxib was the most used NSAIDs (4,9 DHD), followed by ibuprofen (4,0 DHD). Refering to other drugs prescribed for MSP, the prescription rate of tramadol for continuous consumers was RESUMEN Introducción: La alta prevalencia de enfermedades musculoesqueléticas (EME) en determinados grupos de población puede condicionar que el consumo de antiinflamatorios no esteroideos (AINE) sea elevado. El presente estudio pretende identificar a los consumidores continuados de AINE en una cohorte de trabajadores que realizan fundamentalmente tareas de tipo manual, analizando el uso que hacen de otros fármacos indicados en el tratamiento del dolor musculoesquelético (DME). Material y métodos: Estudio observacional retrospectivo, en el que se han analizado los datos, recogidos en la base de consumo farmacéutico Farmasalud, de todos los sujetos de la cohorte AWHS (Aragon Workers Health Study), que presentaron al menos una receta de un AINE durante el año 2016. Se ha calculado la tasa de utilización de AINE, así como el número de dosis diarias definidas (DDD) por 1000 habitantes por día (DHD). Se han identificado los consumidores continuados como aquellos que utilizaron 182 DDD o más. Para este grupo de consumo, se han analizado otros fármacos prescritos que suelen asociarse al tratamiento del DME. Resultados: La tasa de utilización de AINE en la cohorte AWHS en 2016 fue del 41,6 % (IC 95 %: 40,1-42,7 %), siendo mayor en mujeres (47,0 %, IC 95 %: 41,9-52,1 %). El 5,7 % de los usuarios de AINE ORIGINAL DOI: 10.20986/resed.2020.3749/2019

Consumo de fármacos utilizados en el tratamiento del dolor musculoesquético en una cohorte de trabajadores manuales de Zaragoza