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espanolRESUMEN Objetivo: El objetivo de este estudio es evaluar la prevalencia de dolor irruptivo (DI) en pacientes ambulatorios con dolor cronico de origen no oncologico y caracterizar la fisiopatologia, localizacion, intensidad y frecuencia de los episodios de DI. Material y metodos: Estudio observacional, prospectivo y no intervencionista realizado en 16 unidades de dolor ambulatorias de hospitales de Andalucia y Ceuta. Se pregunto a los pacientes consecutivos elegibles si experimentan DI definido como "una exacerbacion transitoria del dolor que ocurre espontaneamente, o en relacion con un desencadenante predecible o impredecible especifico, a pesar del dolor de base estable y controlado". En cada dia de la encuesta, los dos primeros pacientes que confirmaron DI fueron preguntados sobre las caracteristicas clinicas de su PTP (etiologia, inicio, intensidad, frecuencia y tratamiento). Resultados: Se realizo un cribaje a un total de 3209 pacientes con dolor cronico no oncologico para identificar a 1118 pacientes con DI, lo que represento una prevalencia del 36 %. Se obtuvieron las caracteristicas del DI de 350 pacientes: la intensidad media fue de 8,3 (± 1,4) en una Escala Analogica Visual (EVA), con una media de 2 episodios/24 horas (rango 1-5/24 h). El mecanismo del dolor fue mixto en 149 (42,6 %), neuropatico en 91 (26 %) y nociceptivo en 72 (20,6 %) de los pacientes. Se encontro correlacion positiva entre una mayor intensidad de DI con el nivel de dolor basal (r = 0,243, p EnglishABSTRACT Objective: The aim of this study was to evaluate the prevalence of breakthrough pain (BTP) in ambulatory patients with non-cancer chronic pain in Spain and to characterize physiopathology, location, intensity and frequency of BTP episodes. Methods: Prospective, non-interventional, observational study conducted in 16 pain units of hospitals of Andalusia and Ceuta. Eligible consecutive patients were are asked if they experience BTP defined as "a transient exacerbation of pain that occurs either spontaneously, or in relation to a specific predictable or unpredictable trigger, despite stable and controlled background pain". At each survey day, the first two patients reporting BTP were further interrogated on the clinical characteristics of their BTP (etiology, onset, intensity, frequency and treatment). Results: A total of 3,209 patients with non-cancer chronic pain were screened to identify 1,118 patients with BTP, which represented a prevalence of 36 %. BTP characteristics were retrieved from 350 patients: mean BTP intensity was 8.3 (± 1.4) on a Visual Analogue Scale (VAS), with a mean of 2 episodes/24 hour (range 1-5/24 h). Pain mechanism was mixed in 149 (42.6 %), neuropathic in 91 (26 %) and nociceptive in 72 in (20.6 %) of patients. Significant correlation was found between BTP intensity and both higher background pain (r = 0.243, p

Estudio CRONO: prevalencia del dolor irruptivo en pacientes con dolor crónico no oncológico en Andalucía, España.