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Objective. To determine the frequency of production of enterotoxin A and B strains of S.aureus isolated from children with various forms of intestinal dysbiosis. Methods. 74 strains of S.aureus, isolated from the feces of young children with intestinal dysbiosis were studied. 16 strains isolated from children aged 1—6 months, 13 strains — from children aged 6—12 months and 42 strains from children aged 1—3 years. 24 (36,5%) children were an asymptomatic carrier of S.aureus (compensated intestinal dysbiosis), 51 (63,5%) children were diagnosed with symptomatic staphylococcal intestinal dysbiosis. Determination of strains of S.aureus to the production of enterotoxin A (SEA) and B (SEB) was performed by IHT. In this work we used staphylococcal erythrocytic diagnostic tools developed in NIIEM them. NF Gamal. As a control enterotoxigenic strains of S.aureus (producer SEA-FRI-722 and producer SEV S 6715 H) and enterotoxins SEA, SEV company «Serva» (Germany) and enterotoxins SEA, SEV, obtained in the laboratory NIIEM them. N.F. Gamal. Results. 74 enterotoxigenic strains of intestinal S.aureus, isolated from young children with intestinal dysbiosis were analyzed. The ability to produce SEA was detected in 5,3% SEB — in 10,7%, SEA+SEB in 1,3% of the cultures studied. Enterotoxigenic strains isolated from children with normal stool were detected in 16,1%, in children with bowel dysfunction — in 18,2% of cases. Conclusion. SEA and SEB does not play essential role in the development of bowel dysfunction in intestinal dysbiosis. Asymptomatic colonization of enterotoxigenic strains of S.aureus young children can exist.

EntErotoxigEnity of strains of S.aureuS , isolatEd from childrEn with intEstinal dysbiosis