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Utilization of germplasms as medical sources presents a form of traditional wisdom adopted by a particular community which is identical with a hereditary legacy. This paper deals descriptively with ethnobotany aspects of North Sulawesi community (Minahasa, Mongondow and Sangihe tribes) in utilizing natural bioresources from several forest plant species as traditional cancer-curing treatment, which was further proved scientifically through the identification of active ingredients contents and their efficacious toxicity using Brine Shrimp Lethality Test (BSLT) method. Scrutiny results revealed that the local community in North Sulawesi province has prevalently utilized particular portions (e.g. wood, bark, and leaves) of 14 forest plant species for cancer cure and other desease.The herbal extract from the bark of lawang ( Bl) was identified containing alkaloids, while flavonoids was detected in the extract from consecutively lingkube ( Steud) leaves, yantan ( Dc) leaves, ketapang ( L) bark, manumpang ( Jacq) bark, tanduk rusa stems, kayu gimto ( sp) roots, rumput balsam (

KANDUNGAN BAHAN AKTIF DAN TOKSISITAS TUMBUHAN HUTAN ASAL SULAWESI UTARA YANG BERPOTENSI SEBAGAI OBAT