English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Background:  Liver injury is a common reason for drugs to be withdrawn from the market. Treatment options for common liver disease are limited, and therapy with modern medicines may lack effectiveness. Caulerpa lentillifera  may have strong antioxidant systems that protect the plant from oxidative damage caused by the environment. Objectives:  The main objective of this study was to evaluate the hepatoprotective effect of the methanolic extract of C. lentillifera  against acetaminophen-induced liver toxicity in juvenile zebrafish ( Danio rerio ).  Methods:  Juvenile zebrafish (aged 1 – 3 months) were exposed to 10 mikromolar and 25 mikromolar acetaminophen ( N -acetyl-p-aminophenol; APAP) to induce liver damage. C. lentillifera  methanolic extracts (0.01 mg/L, 0.02 mg/L and 0.03 mg/L), were concomitantly added to individual tanks containing 0.01 M or 0.025 M APAP. The positive control group was treated with N- acetylcysteine/NAC (0.01 M) and silymarin (0.01 mg/L, 0.02 mg/L and 0.03 mg/L). Hematoxylin and Eosin (HE juvenile zebrafish; hepatoprotective; drug-induced liver injury (DILI)

jurnal ilmiah farmasi

Evaluation of the hepatoprotective effect of methanolic extract of Caulerpa lentillifera against acetaminophen-induced liver toxicity in juvenile zebrafish (Danio rerio)