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Apis nigrocincta  Smith is a species of honey bee cavity nesting, endemic to Sulawesi.  R esearch that aims to find the composition of the bioactive content of peptides and antibacterial activity of honey bee venom  A. nigrocincta  Smith  has been conducted . Honey bee venom composition  was analyzed using Sodium Dodecyl Sulphate Polyacrylamide Gel Electrophoresis (SDS-PAGE) Method and Spectrophotometer UV-Vis Method. Analysis of antibacterial activity,  was conducted using a modified agar diffusion method .  The results showed that the venom of the honey bee  Apis nigrocincta Smith has five bands of molecules with a molecular weight i.e. 33.54kDa; 21 kDa and 15.43 kDa. The peptide  detected were  hyaluronidase, fosfolipase A, mellitin, lysofosfolipase or antigen 5. Antibacterial activity  was higher  than the control ampisilin and antibiotic streptomycin.

THE CHARACTERISTICS OF BIOACTIVE PEPTIDES AND ANTIBACTERIAL ACTIVITY OF HONEY BEE (Apis nigrocincta) SMITH VENOM, ENDEMIC TO SULAWESI