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When we use carcinostatic compounds such as nitrogen mustard, nitromin, or TEM clinically, some of them prove effective while others prove ineffective, depending on the kinds of tumors. The same thing goes for rat tumors. From this standpoint, the difference in effect of nitromin on these tumors was studied with a view to finding out what is responsible for effectiveness or otherwise of these carcinostatic compounds. When we gave nitromin to the Yoshida-sarcoma,

The influence of nitrogen mustard, nitromin, and TEM on the DNA (desoxyribonucleic acid) of various kinds of tumors.