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Escherichia coli species can lead to a wide range of disease states, notably pneumonia, urinary tract infections (UTIs), septicemia, and soft tissue infections (Adekunle, 2012). Treatment varies depending on the site of infections and it involves the use of a variety of antibiotics. Beta-lactams (β-lactam), especially third-generation cephalosporins and carbapenems may be used as monotherapy or combination therapy with aminoglycosides for treatment of susceptible isolates (Podschun and Ullmann, 1998).

Phenotypic and Genotypic Patterns of Beta-Lactam Resistance among Escherichia coli Clinical Isolates