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One of the most important bacterial diseases worldwide brucellosis has been classified by World Health Organization as world leading neglected zoonotic disease (OIE, 2010). It severely hinders livestock productivity and human health worldwide. Brucella abortus is the main causative organism in bovine. Bovine brucellosis has been reported in virtually all countries where cattle are farmed. The disease is endemic in India, a country that house the world’s largest cattle and buffalo population and produce the most milk in the world.

Study of Outer Membrane Vesicles Isolated from B. Abortus S19 by Bulk Production and Characterization