English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

ABSTRAK Penelitian sebelumnya telah mengungkap efek larvasida ekstrak etanol daun kirinyuh ( Eupatorium inulifolium Kunth.) terhadap larva nyamuk Aedes aegypti . Ekstrak ini selanjutnya dapat dikembangkan dalam bentuk sediaan sand granules sehingga mudah digunakan sebagai larvasida alami. Penelitian ini bertujuan untuk mendapatkan formula sand granules ekstrak etanol daun Eupatorium inulifolium Kunth (EEDE) yang memenuhi standar karakteristik fisik granul dan menguji efek larvasidanya pada larva nyamuk Aedes aegypti. Sand granules EEDE dibuat dengan metode  granulasi basah dengan variasi konsentrasi kollidon (1%-5%), explotab (1%-3%) dan sacharum lactis (78,44%-84,44%). Karakteristik fisik berbagai formula Sand granules EEDE yang diuji adalah kecepatan alir dan sudut diam. Uji efek larvasida dilakukan pada 25 ekor larva instar III nyamuk Aedes aegypti selama 24 jam dengan replikasi sebanyak 5 kali . Hasil penelitian menunjukkan bahwa semua formula Sand granules EEDE (F1-F5) memenuhi standar karakteristik fisik dengan kecepatan alir (16,69-19,35) g/detik dan sudut diam granul 32,94°-35,76°. F1-F5 juga memiliki efek larvasida terhadap larva nyamuk Aedes aegypti dengan persentase kematian larva dalam 24 jam sebesar (33,0-39,2) %. Akan tetapi, efek larvasida tersebut lebih kecil dibandingkan dengan EEDE 670 ppm (49,6%) dan Temefos ® 0,01 ppm (100,0%). Hasil penelitian ini juga menyimpulkan bahwa proses pembuatan sand granules akan menyebabkan penurunan efek larvasida EEDE. Kata Kunci : Daun kirinyuh , efek larvasida, karakteristik fisik, sand granules ABSTRACT Previous studies reported Eupatorium inulifolium Kunth. leaves ethanol extract ( E LEE) have a larvicidal effect on  Aedes aegypti  larvae. This extract can be developed into sand granules formulation, making it easy to use as a natural larvicidal. This study means to obtain the E LEE sand granules formula that meets the granule's physical characteristics standard, and asses it's a larvicidal effect on  Aedes aegypti  larvae. Sand granules of E LEE produced with the wet granulation method. The differences between formulas are variations of Kollidon (1%-5%), Explotab (1%-3%), and Saccharum Lactis (78.44%-84.44%) concentration. The physical characteristics of the various KLEE sand granules formulas observed are flow rate and angle of repose. The assay of the E LEE larvicidal effect was carried out on twenty-five  Aedes aegypti  Instar III larvae for 24 hours with five replications. The results showed that all E LEE sand granules formulas (F1-F5) met the physical characteristics standard, with a flow rate (16.69-19.35) g/sec and an angle of repose 32.94 °-35.76°. F-F5 also had larvicidal effects on Aedes aegypti larvae, with larval mortality within 24 hours (33.0-39.2) %. However, their larvicidal effect is slight compared to E LEE 670 ppm (49.6%) and Temefos ® 0.01 ppm (100.0%). This study also concludes that the process of sand granules preparation will diminish the larvicidal effects of E LEE. Keywords: Kirinyuh leaves, larvacidal effect, physical characteristics, sand granules

Sand Granules Ekstrak Etanol Daun Kirinyuh (Eupatorium inulifolium Kunth.) sebagai Larvasida Alami Pemberantas Demam Berdarah Dengue